Results 201 to 210 of about 286,837 (267)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Pride or backlash? Public attitudes towards the Spanish women's national football team. [PDF]

Front Sports Act Living
Moscoso-Sánchez D, Pasadas-Del-Amo S, Ramis-Moyano R, Trujillo-Carmona M.   +3 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

The impact of discrimination perception on academic burnout of junior college students: the mediating role of belief in a just world and the moderating effect of sense of family obligation. [PDF]

Front Psychol
Du W, Yan Q, Zhang M, Lv X, Zhang M.
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Exploring Pathways Linking Work and Nonwork Factors to Sleep, Fatigue, and Health in Night Shift Nurses: A Structural Equation Modeling Analysis. [PDF]

J Nurs Manag
Jeon BM, Kim SH.
europepmc   +1 more source

The Correlation Between Stress of Conscience and Burnout Among Health Care Personnel at an Acute Care Hospital in Southern Sweden: A Cross-Sectional Study. [PDF]

Scand J Caring Sci
Ekstrand M, Ekwall A, Porter S.
europepmc   +1 more source

General Health (GHQ-28/CGHQ-28) and Psychosocial Risks (COPSOQ-ISTAS21) in Prehospital Emergency Professionals: A Pre-COVID-19 Cross-Sectional Study in Southern Spain. [PDF]

Healthcare (Basel)
Morales-García JA, Ocaña-Peinado FM, Costela-Ruiz VJ, De Luna-Bertos E, Ramos-Torrecillas J, García-Martínez O.   +5 more
europepmc   +1 more source

Does workers' experience of knowledge on emotional demands protect against burnout? [PDF]

BMC Psychol
Pihl-Thingvad J, Andersen DR, Andersen LPS.   +2 more
europepmc   +1 more source

Organizational health factors: multidimensional insights into occupational stress in higher education. [PDF]

Front Psychol
Souto I, Pereira AS, Brito E, Alves P, Marrinhas D.   +4 more
europepmc   +1 more source