Results 121 to 130 of about 391,045 (303)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
AI-Driven Vishing Attacks: A Practical Approach
Engineering ProceedingsToday, there are many security problems at the technological level, especially in telecommunications. Cybercriminals invade and steal data from any system using vector attacks such as phishing through scam mail, fake websites and phone calls. This latter
Fabricio Toapanta +3 more
doaj +1 more source
Toward understanding social engineering
, 2013 There is no doubt that social engineering plays a vital role in compromising most security defenses, and in attacks on people, organizations, companies, or even governments. It is the art of deceiving and tricking people to reveal critical information or
Tian, Yu-Chu +3 more
core
The Social Impact of STEM, Experienced: Studies With an Engineering Design Concept for Smart Devices
, 2019 The government has been allocating multi-billion Dollar budgets to STEM (science, technology, engineering and math) education. Several programs aim to educate girls about STEM and STEAM (STEM and arts).
Wallace, David +1 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A social engineering model for poverty alleviation. [PDF]
Nat Commun, 2020 Chattopadhyay AK, Kumar TK, Rice I.
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Social engineering in social networking sites : phase-based and source-based models
, 2013 Social networking sites (SNSs), with their large numbers of users and large information base, seem to be perfect breeding grounds for exploiting the vulnerabilities of people, the weakest link in security.
Algarni, Abdullah, Xu, Yue
core +1 more source