Results 41 to 50 of about 16,359,512 (299)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Technical Mapping of the Grooming Anatomy Using Machine Learning Paradigms: An Information Security Approach

open access: yesIEEE Access, 2019
In the field of information security, there are several areas of study that are under development. Social engineering is one of them that addresses the multidisciplinary challenges of cyber security.
Patricio Zambrano   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Social Engineering—The Hidden Control

open access: yesProceedings, 2020
The former energy-wasting lifestyles of developed societies can no longer be sustained. In our age, efficiency is the key to continued sustainability. Increasing efficiency requires the use of infocommunication systems and their regulation.
Edina Albininé Budavári   +1 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Ethical Issues in Empirical Studies of Software Engineering [PDF]

open access: yes, 2002
The popularity of empirical methods in software engineering research is on the rise. Surveys, experiments, metrics, case studies, and field studies are examples of empirical methods used to investigate both software engineering processes and products ...
Singer, Janice A.   +3 more
core   +1 more source

Social technologies in the sociological and “non-sociological” dimensions

open access: yesRUDN journal of Sociology
The article explains the historical and logical connection between social technologies and the theory of social technologies: today simply acknowledging this connection is insufficient to understand the content and complexity of the relationships between
V. P. Babintsev
doaj   +1 more source

Development of Game-Based Learning Scenarios for Social Engineering and Security Risk Management for SMEs in the Manufacturing Industry [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2021
With increasing digitization, information security (IS) is becoming an important issue for all employees working in companies and organizations. If the human factor is to be seen as a strength rather than a weakness, appropriate awareness-raising ...
Margit Scholl   +2 more
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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