Results 61 to 70 of about 391,045 (303)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Bibliometric Analysis of the Research Landscape in Human-Computer Interaction in Ibero-America
TecnoLógicasHuman-Computer Interaction (HCI) is a research discipline that optimizes human-machine interfaces. Ibero-America has become a leading region in HCI advances adapted to its unique socioeconomic environment.
Andrés Felipe Solis Pino +4 more
doaj +1 more source
Development of Game-Based Learning Scenarios for Social Engineering and Security Risk Management for SMEs in the Manufacturing Industry [PDF]
Journal of Systemics, Cybernetics and Informatics, 2021 With increasing digitization, information security (IS) is becoming an important issue for all employees working in companies and organizations. If the human factor is to be seen as a strength rather than a weakness, appropriate awareness-raising ...
Margit Scholl +2 more
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Rekayasa Sosial dalam Fenomena Save LGBT
JKG (Jurnal Komunikasi Global), 2018 This research will explore the existence of social engineering agenda in phenomenon SAVE LGBT. This phenomenon is actually a classical social problem. Due to the fact that homosexual and lesbian problems existed in the days of prophets long before humans
Gunawan Saleh, Muhammad Arif
doaj
ChatPhishDetector: Detecting Phishing Sites Using Large Language Models
IEEE AccessLarge Language Models (LLMs), such as ChatGPT, are significantly impacting various fields. While LLMs have been extensively studied for code generation and text synthesis, their application in detecting malicious web content, particularly phishing sites,
Takashi Koide +2 more
doaj +1 more source
Social-Comparison Engineering in Children
, 2019 The data was collected to investigate social-comparison engineering in children.
Bettina Rockenbach (280189) +3 more
core +1 more source
The political, social and economic dimensions of engineering education
, 2023 The social, political, and economic structure of a society influences several aspects of the society, including the education sector and these three areas are often interconnected and affected by similar issues. Engineering, like other
Fomunyam, Kehdinga George
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source