Results 111 to 120 of about 1,199,071 (293)
Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System
Advanced Science, EarlyView.This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi +13 more
wiley +1 more source
Century Services: Year II Evaluation Report on the Social Business Enterprise Model [PDF]
, 2002 The Mid-America Institute on Poverty is conducting a three-year evaluation of Century Services, a social business enterprise operated by Heartland Alliance's Century Place Development Corporation.The evaluation aims to provide: A clear understanding of ...
core
Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
wiley +1 more source
MATEC Web of Conferences, 2017 The rapid development of the mobile internet, mobile communication technology and mobile terminal stimulate demand of mobile application in manufacturing enterprises, which makes the enterprise implement the mobile ERP.
Zuo Cen, Zhang Xumei, Wang Xingshan
doaj +1 more source
Perceptions of Health and Wellbeing Among Employees in a Work Integration Social Enterprise in Sweden. [PDF]
Ann Glob Health, 2023 Macassa G +10 more
europepmc +1 more source
Vocational Training Sector Brief [PDF]
, 2013 This report provides a brief insight on the value chain of the Social Enterprise (SE) vocational training sector in both South and Southeast Asia, highlighting the sector's social impact, innovation, sustainability, and market ...
core
ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment
Advanced Science, EarlyView.ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song +12 more
wiley +1 more source
Social enterprise in health organisation and management: hybridity or homogeneity? [PDF]
, 2003 The purpose of this paper is to reflect on social enterprise as an organisational form in health organisation and management.\ud \ud The paper presents a critique of the underlying assumptions associated with social enterprise in the context of English ...
Millar, Ross
core
Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response
Advanced Science, EarlyView.This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai +7 more
wiley +1 more source