Results 111 to 120 of about 5,180,562 (321)

Managing care environments: reflections from research and practice [PDF]

open access: yes, 2007
This chapter considers the role of senior staff in managing the use of space and the physical environment within care settings. These day and residential settings come under the broad umbrella of social work and social care but the care may also be ...
Peace, Sheila, Reynolds, Jill
core  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

What Strategies do Companies use to Transform Employees into Social Media Advocates? [PDF]

open access: yes, 2015
There is an overwhelming consensus among researchers that employees have the potential to become excellent social ambassadors for their company. Readers of social media sites believe employees to be credible representatives of their organization, and ...
Drori, Elad
core   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Social status, environment, and atherosclerosis in cynomolgus monkeys. [PDF]

open access: bronze, 1982
Jay R. Kaplan   +4 more
openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

River basin planning project: social learning (Science Report SC050037/SR1) [PDF]

open access: yes, 2005
This report documents the findings of a 12-month Environment Agency science project on social learning for river basin planning. Our aim was to use social learning approaches and soft system methods to inform the development of the River Basin Planning ...
Blackmore, Chris   +2 more
core  

Home - About - Disclaimer - Privacy