Results 101 to 110 of about 5,661,520 (295)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Artificial Intelligence (AI) holds promise as a technology that can be used to improve government and economic policy-making. This paper proposes a new research agenda towards this end by introducing Social Environment Design, a general framework for the use of AI for automated policy-making that connects with the Reinforcement Learning, EconCS, and ...
Zhang, Edwin +8 more
openaire +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Use of Questions to Facilitate Social Learning in a Web 2.0 Environment [PDF]
, 2011 Online social learning involves distributed learners interacting through the use of Web 2.0. In many cases, Web 2.0 interactions are limited to information exchange and do not provoke knowledge construction.
Ferguson, Rebecca
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
STRESS FACTORS OF THE PRODUCTION ENVIRONMENT IN ACTIVITY OF BANK EMPLOYEES
RUDN Journal of Ecology and Life Safety, 2015 Article is devoted to studying influence of factors of the social environment on human ecology. On selection of the workers’ bank sphere influence a stress factors of the production environment on psycho- emotional and professional health of employees ...
N I Kachanovetskaya
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Effect of Haptic Feedback on Basic Social. Interaction within Shared Virtual Environments [PDF]
, 2008 This paper describes an experiment that studies the effect of basic haptic feedback in creating a sense of social interaction within a shared virtual environment (SVE).
Eslava, Victor +6 more
core +1 more source
Analysis of children′s well-being from the perspective of family–school–community collaboration
Zhongguo gonggong weishengObjectiveTo understand the influence of family, school, and community social environments on children′s perceived well-being, to explore the key indicators that affect children′s well-being, and to provide suggestions and references for building child ...
Wenkui LU +7 more
doaj +1 more source