Results 81 to 90 of about 18,448,700 (250)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Social Work and the Natural Environment: Embedding Content Across Curricula
, 2018 Social work is a profession focused on people within their environments. This is reflected in codes of ethics, where our shared mandate is to work towards individual wellbeing and social change. Recently, social work literature has promoted green and eco-
Boddy, Jennifer +5 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The Role of Classroom Management in Enhancing Learners’ Academic Performance: Teachers’ Experiences
Studies in Learning and TeachingLearners’ academic performance is one of the most imperative elements of the classroom and a core responsibility of teachers as well as schools. Thus, it is imperative to manage a classroom in a way that is conducive to teaching and learning that can ...
Nadeem Ahmed, du Plessis Pierre
doaj +1 more source
Social carry-over effects on non-social behavioral variation: mechanisms and consequences
Frontiers in Ecology and Evolution, 2015 The field of animal personality is interested in decomposing behaviors into different levels of variation, with its present focus on the ecological and evolutionary causes and consequences of expressed variation.
Petri Toivo Niemelä +1 more
doaj +1 more source
Annual Report on the Environment in Japan
, 2009 The white paper on comprehensive environmental policy describes the role of Japan's economy in a sound global environment. In the first part, the report describes current the environmental conditions of the Earth and of Japan, human activities in Japan ...
[Japan] Ministry of the Environment
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2008 No known reports between 2003 and 2007 2008 onward published biennially "The publication of the 2008 Kansas Environment report represents the return to a biennial report for the Division of Environment at the Kansas Department of Health and Environment."
Kansas. Department of Health and Environment
core +1 more source
Children, 2019 Physical activity during early childhood is a prerequisite for healthy development in many cases. The aim of this study was to assess the relationships of social modelling and support from parents, peers, and siblings and domain-specific physical ...
Anne Kerstin Reimers +6 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source