Results 81 to 90 of about 5,661,520 (295)

Sociological Narrative of Suicidal Behavior Among Older People

open access: yesClinical Interventions in Aging, 2021
Novel Lyndon,1 Hazita Azman,2 Rosniza Aznie Che Rose,3 Mohd Fuad Mat Jali3 1Anthropology and Sociology Programme, Faculty of Social Sciences and Humanities, Universiti Kebangsaan Malaysia, Bangi, Selangor, 43600, Malaysia; 2Centre for Literacy and ...
Lyndon N   +3 more
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The Value of the Nonprofit Environment Field in Illinois: A Social Return on Investment Analysis with Donors Forum [PDF]

open access: yes, 2015
This Social Return on Investment (SROI) analysis compares the public and private investment into the Illinois nonprofit environment field to the social, environmental, and economic value it creates for people who live in Illinois and for society as a ...
Amy Terpstra, Jennifer Clary
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Secure Mobile Social Networks using USIM in a Closed Environment [PDF]

open access: yes, 2012
Online social networking and corresponding mobile based applications are gaining popularity and now considered a well-integrated service within mobile devices.
Gehrmann, Christian
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

What Strategies do Companies use to Transform Employees into Social Media Advocates? [PDF]

open access: yes, 2015
There is an overwhelming consensus among researchers that employees have the potential to become excellent social ambassadors for their company. Readers of social media sites believe employees to be credible representatives of their organization, and ...
Drori, Elad
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Social Media in the Dental School Environment, Part B: Curricular Considerations [PDF]

open access: yes, 2015
The goal of this article is to describe the broad curricular constructs surrounding teaching and learning about social media in dental education. This analysis takes into account timing, development, and assessment of the knowledge, skills, attitudes ...
Chambers, David   +6 more
core   +2 more sources

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