Results 71 to 80 of about 5,661,520 (295)

How Can Overlooking Social Interactions, Space Familiarity or Other “Invisible Landscapes” Shaping Animal Movement Bias Habitat Selection Estimations and Species Distribution Predictions?

Ecology and Evolution
Species' future distributions are commonly predicted using models that link the likelihood of occurrence of individuals to the environment. Although animals' movements are influenced by physical and non‐physical landscapes, for example related to ...
Romain Dejeante, Rémi Lemaire‐Patin, Simon Chamaillé‐Jammes   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Interactions between neighborhood social environment and walkability to explain Belgian older adults' physical activity and sedentary time [PDF]

, 2016
This study examined associations between neighborhood social factors and physical activity (PA) and sedentary behavior (SB) in older adults. Furthermore, possible moderating effects of neighborhood walkability were explored.
De Bourdeaudhuij, Ilse, Deforche, Benedicte, Van Cauwenberg, Jelle, Van de Weghe, Nico, Van Dyck, Delfien, Van Holle, Veerle   +5 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Body Mass Index and its Predictive Factors in Rasht, Iran

Payesh, 2020
Objective (s): Body mass index (BMI) is one of the major contributors to the spread of non-communicable diseases that it is affected by various factors such as demographic variables and living environment.
Abolfazl Etebarian Khorasgani, Atefeh Ghanbari Khanghah, Sajad Mirhasani, Seyed Hamid Sharif Nia   +3 more
doaj  

Environmental problems - are the focus of attention in the development of New Uzbekistan [PDF]

BIO Web of Conferences
This article discusses issues related to environmental problems, issues related to air pollution and the negative impact of industrial enterprises on the environment, ensuring environmental safety, and also gives an opinion on research work carried out ...
Yadgarova Gulbahor, Bakhrieva Nargiza
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Effect Of Omitted Spatial Effects And Social Dependence In The Modelling Of Household Expenditure For Fruits And Vegetables [PDF]

, 2014
We find the omitted elements of the external environment affect negatively the estimates for other spatial (social) effect parameters. Especially, we notice the overestimation of the random effect variance when the social dependence is omitted and the ...
Dong, Guanpeng, Harris, Richard, Łaszkiewicz, Edyta   +2 more
core   +2 more sources