Results 111 to 120 of about 5,661,520 (295)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The Interplay between Social Environment, Perceived Stress and Coping among Students: A Case of Malawi University of Business and Applied Sciences

International Journal of Educational Psychology
  The social environment plays a crucial role in shaping students' learning experiences and mental well-being, ultimately impacting their academic performance.
Sufyan Rashid, Flemmings Fishani Ngwira, Janet Chikoja   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The Relationship of CSR and Financial Performance: New Evidence From Indonesian Companies [PDF]

, 2012
The research objectives of the study are to investigate whether there are any positive relationships between CFP and CSR under the slack resource theory and to investigate whether there are any positive relationships between ...
Fauzi, Hasan, Idris, Kamil M.
core   +1 more source

Atividade física e percepção do ambiente em idosos: estudo populacional em Florianópolis

Revista de Saúde Pública
OBJETIVO: Estimar a prevalência da prática de atividade física de lazer em idosos e analisar sua associação com a percepção do ambiente. MÉTODOS: Estudo de base populacional, transversal, conduzido com 1.656 indivíduos com 60 anos ou mais residentes na ...
Maruí Weber Corseuil Giehl, Ione Jayce Ceola Schneider, Herton Xavier Corseuil, Tânia Rosane Bertoldo Benedetti, Eleonora d'Orsi   +4 more
doaj  

The social environment

The social environment of domesticated pigs is clearly different from the natural social environment of their wild counterparts. This difference could frustrate pigs and, thereby, lead to damaging behaviours such as tail biting. However, much about this presumed relationship between tail biting in pigs and the social environment is unknown.
Reimert, Inonge, Ursinus, Winanda W.
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Multifunctionality: Environment versus Rural Viability in Social Optima [PDF]

We examine policy implications of including rural viability to the notion of multifunctional agriculture. We assume that rural viability refers predominantly to the number of people living in rural areas to keep the infrastructure and living conditions ...
Lankoski, Jussi E., Ollikainen, Markku
core   +1 more source

The relationship between physical segregation and social marginalisation in the urban environment [PDF]

, 2005
This paper posits a relationship between the urban location of immigrant quarters and the likelihood that the inhabitants of such areas will improve themselves economically.
Vaughan, L
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source