Results 31 to 40 of about 19,248,443 (230)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Early social environment influences the behaviour of a family-living lizard

Royal Society Open Science, 2017
Early social environment can play a significant role in shaping behavioural development. For instance, in many social mammals and birds, isolation rearing results in individuals that are less exploratory, shyer, less social and more aggressive than ...
J. Riley, D. Noble, R. Byrne, M. Whiting
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The meaning of labour pain: how the social environment and other contextual factors shape women’s experiences

BMC Pregnancy and Childbirth, 2017
BackgroundThe majority of women experience pain during labour and childbirth, however not all women experience it in the same way. In order to develop a more complete understanding of labour pain, this study aimed to examine women’s experiences within ...
Laura Y. Whitburn, L. Jones, Mary-Ann Davey, R. Small   +3 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Anxious to see you: Neuroendocrine mechanisms of social vigilance and anxiety during adolescence. [PDF]

, 2020
Social vigilance is a behavioral strategy commonly used in adverse or changing social environments. In animals, a combination of avoidance and vigilance allows an individual to evade potentially dangerous confrontations while monitoring the social ...
Cassano G. B., Gegenhuber B., Hollingworth S. A., Marler C. A., Park J., Pickett C. L., Williamson C. M.   +6 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A qualitative study of stakeholders' perspectives on the social network service environment [PDF]

, 2014
Over two billion people are using the Internet at present, assisted by the mediating activities of software agents which deal with the diversity and complexity of information.
Arazy O., Baran P., Baym N., Bazeley P., Bignell K., Boyd D., Bryman A., Burgess R., Burns N., Chinn P., Curasi C., David M., Easterby-Smith M., Elgesem D., Franklin S., Freeman A., Gilbert D., Graham M., Haag S., Hojung Kim, International Telecommunication Union, Joseph Giacomin, Kothari C., Krippendorff K., Lippay L., Marci C., Mavridis N., Melville P., Miller A., Nissenbaum H., Nissenbaum H., Norman D., Ofcom, Organisation for Economic Co-operation and Development, Preibusch S., Ramparany F., Robert Macredie, Robson C., Saunders M., Spinello R., Staniford L., Stanton N., Sterling B., Strauss A., Suchman L., Thaler R., Westin A., Working Group on Internet Governance, Zarsky T.   +48 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source