Results 131 to 140 of about 504,419 (304)

The economic burden of anesthetic-related adverse events: a systematic review and empirical analysis

open access: yesBMC Anesthesiology
Background While extensive evidence is available on the adverse events (AEs) related to agents used to perform general anesthesia and procedural sedation from a clinical standpoint, much less is known about their economic impact on healthcare systems ...
Patrizio Armeni   +5 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Political journalism in transition: Western Europe in a comparative perspective

open access: yes, 2014
The 21st century has already seen dramatic changes affecting both journalism and politics. The rise of a range of new digital and networked communication technologies combined with the stagnation and decline of many traditional mass media has had a ...

core   +2 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

A simulation of social pensions in Europe [PDF]

open access: yes, 2012
The aim of this paper is to evaluate the impact in terms of poverty and cost of the introduction of social (or non-contributory) pensions in Europe. We use data from the household survey EU-SILC and focus on 17 countries. We simulate – in a static framework – the introduction of two social pension schemes: universal and means tested social pensions. We
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Protection sociale en Europe, protection sociale et Europe

open access: yesCalenda, 2013
Quelle influence des orientations économiques et du droit européen sur les systèmes de protection sociale nationaux ? Quelle place pour les systèmes et services sociaux dans le marché intérieur ? Quelles évolutions des systèmes nationaux de protection sociale  dans la crise ?
openaire   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Reducing precarious work in Europe through social dialogue : the case of France

open access: yes, 2016
Ce rapport résulte d’une étude réalisée dans 6 pays (Allemagne, Danemark, Espagne, France, Grande-Bretagne et Slovénie) pour le compte de la DG emploi de la Commission européenne et présente le cas de la France.
Kornig, Cathel   +2 more
core  

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