Results 101 to 110 of about 2,329,139 (297)

The Digital Archive of Huhugam Archaeology and the Reuse of Archaeological Information

open access: yesAdvances in Archaeological Practice
The reuse of information derived from past archaeological investigations is integral to contemporary research practices. Yet, archiving practices of many (but not all) scholars, cultural resource managers, and public agencies often fall short of meeting ...
Christopher Nicholson   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

„FILOSOFIA” MODERNIZĂRII SOCIETĂȚII RURALE ROMÂNEȘTI. 1864-1918 [PDF]

open access: yesRevista de Știinţe Politice şi Relaţii Internaţionale, 2018
The issue that we are interested in this study focuses on the ideas of the Romanian thinkers regarding the state construction of the Romanian identity and its relationship with the institutional system that was to manage the problem of the peasant ...
ENACHE TUȘA
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Radiocarbon-Refined Archaeological Chronology and the History of Human Activity in the Southern Tarim Basin

open access: yesLand
Famous for Taklimakan, the world’s second largest sandy desert, the Tarim Basin in Xinjiang has long attracted researchers from various fields to investigate its paleoenvironment and antiquity.
Xiaofang Ma, Xingjun Hu, Menghan Qiu
doaj   +1 more source

Information-Mental and Socio-Evolutionary Contexts of the Dynamics of War and Peace [PDF]

open access: yesГуманитарный вектор
The fi rst decades of the XXI century are marked by processes of turbulence, multiple tensions and dramatic events. In this context, the issues of geopolitics, war and peace play a particularly signifi cant role.
Nikolai S. Rozov
doaj   +1 more source

The diplomat's dilemma: Maximal power for minimal effort in social networks

open access: yes, 2008
Closeness is a global measure of centrality in networks, and a proxy for how influential actors are in social networks. In most network models, and many empirical networks, closeness is strongly correlated with degree.
A Barrat   +26 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Tradeoffs in viral fitness driven by alternative entry pathways

open access: yesmBio
Enveloped viruses can enter cells either through endocytosis or by direct fusion with the plasma membrane. The latter pathway often leads to syncytia formation, caused by the fusion of infected cells with neighboring receptor-bearing cells.
Marc Carrascosa-Sàez   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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