Results 231 to 240 of about 14,672,329 (357)

Cellular allorecognition and its roles in Dictyostelium development and social evolution. [PDF]

Int J Dev Biol, 2019
Kundert P, Shaulsky G.
europepmc   +1 more source

Next-Practice Leadership Integrating Human-Centered Management with Digital Evolution and Social Dynamics [PDF]

Evans Momanyi Getembe
openalex   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The benefits of grouping as a main driver of social evolution in a halictine bee. [PDF]

Sci Adv, 2018
Ohkubo Y, Yamamoto T, Ogusu N, Watanabe S, Murakami Y, Yagi N, Hasegawa E.   +6 more
europepmc   +1 more source

Ranking of Countries for Accelerated Social Evolution in Conditions of Global Crisis

Andriy Nosalsky
openalex   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Hamilton's rule is essential but insufficient for understanding monogamy's role in social evolution. [PDF]

R Soc Open Sci, 2019
Nonacs P.
europepmc   +1 more source

Corrigendum to “Evolution of interpreting as a social practice in China during the past four decades. An analysis of Chinese discourse on interpreting through the lens of social practice theory”

openalex   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

The social evolution of sleep: sex differences, intragenomic conflicts and clinical pathologies. [PDF]

Proc Biol Sci, 2019
Faria GS, Varela SAM, Gardner A.
europepmc   +1 more source