Results 81 to 90 of about 2,480,054 (347)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
On the Viability of Gift Exchange in a Market Environment [PDF]
Is gift-exchange inevitably to be crowded out by impersonal market exchange? The presence of a thick-market externality indicates that this is indeed likely to be the case. But reciprocity or gift-exchange induces social relations.
Klundert, T.C.M.J. van de +1 more
core +1 more source
The Future of Social Marketing [PDF]
, 2010 {Excerpt} Social marketing is the use of marketing principles and techniques to effect behavioral change. It is a concept, process, and application for understanding who people are, what they desire, and then organizing the creation, communication, and ...
Serrat, Olivier
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
M@n@gementThis study analyzes the relationship between training and development (T&D) and individual performance. Drawing insights from human capital theory and social exchange theory, we hypothesize that the relationship between employee T&D perceptions and role ...
Kristine Tamayo-Verleene +3 more
doaj +1 more source
Social Exchange and Common Agency in Organizations [PDF]
We study the relation between formal incentives and social exchange in organizations where employees work for several managers and reciprocate a manager’s attention with higher effort.
Hein Roelfsema, Robert Dur
core
The formation of share market prices under heterogeneous beliefs and common knowledge
, 2011 Financial economic models often assume that investors know (or agree on) the fundamental value of the shares of the firm, easing the passage from the individual to the collective dimension of the financial system generated by the Share Exchange over time.
Biondi, Yuri +2 more
core +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Teacher and student psychological contract: a review of research
Вестник Мининского университетаIntroduction. The article presents a theoretical analysis of the relationships that develop between participants in the educational process. The main idea is that teaching and upbringing are neither a one-sided, purposeful influence of a teacher on a ...
M. A. Gagarina
doaj +1 more source
Equity Theory Ratios as Causal Schemas
Frontiers in Psychology, 2016 Equity theory approaches justice evaluations based on ratios of exchange inputs to exchange outcomes. Situations are evaluated as just if ratios are equal and unjust if unequal.
Alexios Arvanitis, Alexandra Hantzi
doaj +1 more source