Results 201 to 210 of about 1,821,326 (334)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Children's Reasoning about Challenging Social Exclusion of Peers with Learning Difficulties. [PDF]

Int J Behav Dev
Barth C, Killen M, Grütter J.
europepmc   +1 more source

Exposure to and Self-Perceptions of the Risk of Discrimination and Social Exclusion in Access to Public Goods, Media, Healthcare and Employment

, 2020
Svetlana D. Hristovа, Valentina Milenkova   +1 more
openalex   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Impact of social exclusion on salivary progesterone and estradiol in women with borderline personality disorder. [PDF]

Borderline Personal Disord Emot Dysregul
Barthauer M, Graumann L, Cho AB, Kulakova E, Deuter CE, Wolf OT, Hellmann-Regen J, Roepke S, Otte C, Wingenfeld K.   +9 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Investigation of attachment social exclusion and risky behaviors in adolescents. [PDF]

BMC Psychol
Sezer F, Gürtepe A.
europepmc   +1 more source

Exclusion in the free play : Free play and social interaction

, 2023
Bjurbäck, Linda, Olsson, Caroline
openalex   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Mechanisms underlying the alleviation of negative emotions from social exclusion by interpersonal emotion regulation. [PDF]

Sci Rep
Zhu Z, Zhou M, Wang M, Pu J, Tao Y, Ma X.   +5 more
europepmc   +1 more source