Results 111 to 120 of about 7,075,027 (297)

Demographical condition of neonates with congenital abnormalities under Birjand city health centers during 2007-2012

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2014
Background and Aim: Along with extensive control of communicable diseases and decrease in their prevalence, congenital anomalies (CA) has grasped much attention in recent years. Almost 20% of babies’ mortality under one year of age is associated with CA.
Zahra Amini Nasab   +4 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Charting the landscape of rail human factors and automation: A systematic scoping review

open access: yesTransportation Research Interdisciplinary Perspectives
As railway systems in Europe move towards increased integration and automation, understanding the human factors implications is critical. This systematic scoping review examines research on human factors and automation in railways, with a focus on ...
Sarah A. Kusumastuti   +3 more
doaj   +1 more source

An Examination of the Occurrence of Divorce and Social and Demographic Factors within Chicago [PDF]

open access: yes, 2013
This research looks at the occurrence of divorce among Cook County-Chicago census tracts from data gathered from the 2006-2010 American Community Survey (ACS) of the U.S. Census Bureau.
Hahn, Louise
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Karakteristik Sosial Demografi dan Faktor Pendorong Peningkatan Kinerja Kader Posyandu [PDF]

open access: yes, 2014
Posyandu is one of the community participation approach in health sector that is managed by cadres, with the main problem arises is the declining number of visits of mothers of infants and toddlers. The aimed of this research were to analyze the level of
Simanjuntak, M. (Megawati)
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy