Results 221 to 230 of about 19,778,298 (257)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Memoria de actividades del Consejo Económico y Social de Aragón.: 2017 [PDF]

open access: yes, 2017
Consejo Económico y Social de Aragón.   +1 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Memoria de actividades del Consejo Económico y Social de Aragón.: 1996 [PDF]

open access: yes, 1996
Consejo Económico y Social de Aragón.   +1 more
core  

Social Factors Associated with Sudden Unexpected Infant Death. [PDF]

open access: yesAcad Pediatr
Deutsch SA   +3 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Associations between social factors and spinal pain-related disability in people with back pain and/or neck pain. [PDF]

open access: yesAnn Med
Bijker L   +6 more
europepmc   +1 more source

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