Results 61 to 70 of about 1,726,095 (357)
What are the barriers to investing in social enterprises? An investigation into the attitudes and experiences of social entrepreneurs in the United Kingdom [PDF]
, 2013 The ongoing global economic crisis and the restrictions that this is having on government expenditure has meant that current UK policy is being directed at trying to end the grant dependency that currently exists in the third sector.
Denny, Simon +2 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Social sector expenditures and rainy-day funds [PDF]
Gonzalez and Paqueo examine the effects of budget stabilization funds--often called rainy-day funds--on the volatility of social spending and, for contrast, on nonsocial sector spending. They analyze the rainy-day funds of U.S. states.
Gonzalez, Christian Y. +1 more
core
A guide to finance for Social Enterprises in South Africa [PDF]
, 2011 The global economic crisis and its aftermath deepen the challenge of decent employment creation. The Global Jobs Pact developed in response to the crisis sets out a framework that ensures linkages between social progress and economic development. In this
Jack Breslauer
core
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
"Borrowing Alone: The Theory and Policy Implications of the Commodification of Finance" [PDF]
Over the past 20 years, finance has become commodified. Firms increasingly obtain finance from securities markets, instead of borrowing from commercial banks with which they have long-term relationships, while Fannie Mae and Freddie Mac package a growing
Greg Hannsgen
core +3 more sources
Planning and Financing in the Social Development
International Journal of Economics and Business Administration, 2019 Purpose: Determining the purpose, content, appropriation, features of the program-target and design-target methods of planning and financing in the social sphere and the ways of their further development. Design/Methodology /Approach: In modern conditions of economic and financial uncertainty in the social sphere, reform changes, aimed at improving the
openaire +3 more sources
The evaluation of welfare under alternative models of higher education finance [PDF]
A model is developed which allows us to examine the welfare effects of alternative methods of financing access to higher education. Under an extreme specification of the social welfare function, it is shown that it does not matter whether higher ...
Geraint Johnes
core +1 more source
Business Models for Sustainable Finance: The Case Study of Social Impact Bonds [PDF]
, 2019 Business models for sustainability (BMfS) are relevant topics on research agendas, given their orientation toward sustainability issues. However, traditional versions of these models are often ill-equipped at solving complex social problems. Cross-sector
Chiappini, Helen +3 more
core +1 more source