Results 141 to 150 of about 165,151 (308)

Global analysis of social learning’s archetypes in natural resource management: understanding pathways of co-creation of knowledge

Humanities & Social Sciences Communications
Although social learning (SL) conceptualization and implementation are flourishing in sustainability sciences, and its non-rigid conceptual fluidity is regarded as an advantage, research must advance the understanding of SL phenomenon patterns based on ...
Michelle Bonatti, Marcos Lana, Leonardo Medina, Paul Chevelev, Carla Baldivieso, Carla Erismann, Pia Gleich, Tatiana Rodriguez, Luca Eufemia, Teresa da Silva Rosa, Juliano Borba, Custodio Matavel, Sandro Schlindwein, Ray Ison, Klaus Eisenack, Jon Hellin, Grazia Pacillo, Vincent Vadez, Jérôme Bossuet, Aleksandra Dolinska, Stefan Sieber   +20 more
doaj   +1 more source

"Fluidity in Communication Order": Participatory Culture in Social Media during Kerala Floods

, 2020
Recent studies have noted, Remediation of Postmodernism in a digital space thrives to participatory culture, as the margin between creator/user authority/public has blurred. This project discusses the glimpses of the Kerala floods in 2018 and 2019, showing how social media is facilitating the diminishing hierarchical communication structure of ...
openaire   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The Postmodern "˜Turn' in Social Work: The Challenges of Identity and Equality

Social Work and Society, 2007
Diversity and demands for equality have challenged fixed notions of identity amongst the diverse populations of Europe. This development has prompted discourses about the significance of fluidity and multiplicity in identities that have given ...
Lena Dominelli
doaj   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Towards modelling social fluidity I: Theory of social fluidity and theories of complexity

Athenea Digital. Revista de pensamiento e investigación social, 2014
Fernando J. García Selgas, Antonio García Olivares   +1 more
openaire   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Tuning in: diasporas at the BBC World Service

, 2011
This article looks at diaspora through the transformations of an established public service broadcaster, the BBC World Service in a fast changing landscape of global broadcasting, by considering some of the findings of the AHRC-funded Tuning In: Contact ...
Woodward, Kath
core