Results 171 to 180 of about 1,533,792 (313)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Bulletin of the international institute of social history.
Voortgezet als: International review of social ...
International institute of social history Amsterdam
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SOCIAL HISTORY AND THE TEACHING OF HISTORY.
Clio: Revista de Pesquisa Histórica, 1998 This article deals with the contribution of Social History to teaching and research in History. It seeks to examine from the theoretical and methodological point of view the implications this entails for the professionals involved with this perspective of history, and alerts to some of its developments regarding the teaching of History and its practice
openaire +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Standard in South African English and its Social History
This study of the South African variety of English is an exercise in the sociology of language conducted mainly within the conceptual framework and methodology created by William Labov. It accepts that social process and social structure are reflected in
Lanham, Len W., MacDonald, C.A.
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The WHOLE (We Humanize the One-Liner for Everyone) Patient Project-Re-Centering Social History in Oral Case Presentations. [PDF]
J Grad Med EducTure A, Didwania A, Dolan B.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Towards a social history of European integration. [PDF]
Eur Rev Histvan de Grift L, Leucht B.
europepmc +1 more source
Head and neck cancer risk calculator (HaNC-RC)-V.2. Adjustments and addition of symptoms and social history factors. [PDF]
Clin Otolaryngol, 2020 Tikka T +7 more
europepmc +1 more source