Results 161 to 170 of about 1,533,792 (313)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2017 In August, 2016 I was walking between my accommodation and a conference venue on my way to deliver a lecture on social work history when I came across an art installation with the phrase ‘the future has a long history’, which I captured in the above ...
Vicary, Sarah
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Social SecurityThe International Labour and Radical History Pamphlet Collection consists of over 2200 pamphlets representing a broad spectrum of leftist opinion, including communists, socialists, liberal reformers, trade unionists, civil libertarians and
Fabian Society (Great Britain).Social Security Sub-Committee
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This book examines women’s activism in and beyond Central and Eastern Europe and transnationally within and across different historical periods, political regimes, and scales of activism.
core +1 more source
Evaluating documentation of social history in paediatric medical notes at a regional paediatric centre - a quality improvement initiative. [PDF]
BMC Pediatr, 2020 Foley DJ +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The Social History of Disaster Victim Identification in the United States, 1865 to 1950. [PDF]
Acad Forensic Pathol, 2020 Daniel V.
europepmc +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source