Results 191 to 200 of about 15,522,800 (401)

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

open access: yesMolecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda   +3 more
wiley   +1 more source

A tale of two towns: Water provision and management in the towns of Beaufort West and Vanrhynsdorp, c. 1900–1970

open access: yesContree
The Karoo region of South Africa receives some of the lowest annual precipitation in South Africa. The towns of Beaufort West and Vanrhynsdorp share a history of unreliable water supplies, coupled with extreme poverty that left a large section of the ...
Wessel P. Visser, Daniel R. Rademan
doaj   +1 more source

Menorah Review (No. 54, Winter, 2002) [PDF]

open access: yes, 2002
Halakha, Hermeneutics and History -- Go -- Dialogue in Pursuit of Social Action -- Dream Joggings -- Rabbis, Society and Historiography -- Was Herod a Jew?

core   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

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