GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda+15 more
wiley +1 more source
A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression
Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song+11 more
wiley +1 more source
The Servants of Power: A History of the Use of Social Science in American Industry
Edward C. Kirkland, Loren Baritz
openalex +3 more sources
Opioid pharmacovigilance: A clinical-social history of the changes in opioid prescribing for patients with co-occurring chronic non-cancer pain and substance use. [PDF]
Knight KR+6 more
europepmc +1 more source
Select bibliography of contributions to economic and social history appearing in Scandinavian Books, Periodicals, and Year-Books, 1968 [PDF]
Niels Thomsen+3 more
openalex +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla+4 more
wiley +1 more source
A Social History of Ascariasis in the 1960s Korea : From a Norm to a Shameful Disease. [PDF]
Jung J, Park Y, Kim OJ.
europepmc +1 more source
My Opinion to Separate Geography and History from Social Studies
Bunichi Hibino
openalex +2 more sources
Wasps: An Account of the Biology and Natural History of Solitary and Social Wasps [PDF]
A. S. Menke
openalex +1 more source