Results 61 to 70 of about 5,668,569 (360)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Digital ethnography, resistance art and communication media in Iran [PDF]
, 2013 Iranian visual materials relating to the presidential election crisis have the potential to become the sites of analysis and debate for fields as diverse as history, visual history, memory and post-memory, or trauma studies.
Khosronejad, Pedram
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
E3S Web of Conferences, 2017 The paper presents an analysis of the impact of life quality at the level of interpersonal dialogue in legal practice of mining regions as the ratio of different subjects there characterizes social-and-cultural environment in general.
Zolotukhin Vladimir +4 more
doaj +1 more source
The Impact of the Economic Crisis on Social Policy in Interwar Poland
Studies in Logic, Grammar and Rhetoric, 2021 The aim of this paper is to determine how the economic crisis, and the ad hoc attempts made by the authorities to counteract it, affected the Polish society and, above all, to prepare a multidimensional analysis of how the crisis impacted systemic ...
Grata Paweł
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Belgian social law and its journals: a reflected history [PDF]
, 2015 Through the analysis of the emergence of contemporary social law, Bruno Debaenst stresses the multiple links resulting from the creation of a new field in law and its specialized journals.
Debaenst, Bruno
core +1 more source
The Big Squeeze: A Social and Political History of the Controversial Mammogram [PDF]
, 2012 [Excerpt] The Big Squeeze: A Social and Political History of the Controversial Mammogram chronicles the often turbulent history of screening mammography since its introduction in the early 1970s. This book makes five key points.
Reynolds, Handel, MD
core +2 more sources