Results 71 to 80 of about 5,668,569 (360)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Social History of a Genre: Kathas across Languages in Early Modern North India [PDF]

open access: yes, 2017
Tales are ubiquitous in the literary culture of pre-modern North India, as elsewhere, and they come in all shapes, languages and inflections. For this reason, tracking them allows us to travel into and across most of the milieux of this multilingual ...
Orsini, Francesca
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Trade, urban hinterlands and market integration, 1300-1600: a summing up [PDF]

open access: yes, 2000
Paper given at a conference organised by the Centre for Metropolitan History and supported by the Economic and Social Research Council, 7 July ...
Dyer, Christopher
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A historical analysis of health services in Medan and the tobacco plantation areas of East Sumatra during the Dutch colonial period

open access: yesCogent Arts & Humanities
Medan, formerly known as Deli City, developed in connection with the expansion of Deli tobacco companies in East Sumatra. Historic buildings scattered throughout the city reflect the colonial legacy of the plantation economy, with hospitals among the ...
Wasino Wasino   +4 more
doaj   +1 more source

Mobile App in Health: Improving User Awareness Regarding Own Health

open access: yesScience & Philosophy, 2017
Knowledge is more and more a strategic resource for health organizations while information & communication technology earns an important role for sharing knowledge and information among people in and out organizations.
Rocco Reina   +2 more
doaj   +1 more source

Interrelations between After-School Settings and the Delinquency and Emotional-Behavioral Problems of Elementary School Children: Findings from Fragile Families and Child Wellbeing Study

open access: yesSocial Sciences, 2020
Even though there are different types of after-school settings, numerous studies have focused on formal after-school settings (i.e., after-school programs or ASPs) and their association with children’s academic, physical, and social-emotional behaviors ...
Hyejoon Park   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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