Results 41 to 50 of about 3,143,393 (310)

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Under the Conditions of Non-Agenda Ownership: Social Media Users in the 2019 Ukrainian Presidential Elections Campaign [PDF]

open access: yesCEUR Workshop Proceedings. Vol 2392: Proceedings of the 1st International Workshop on Control, Optimisation and Analytical Processing of Social Networks, COAPSN-2019, 2019, 2019
Owing to its history and challenging circumstances, social networks community in Ukraine is a very interesting polygon for the study of communications in the constantly changing environment, especially in the political discourse. This unique environment requires three dimensions to ascertain the political position of its participant.
arxiv  

Primary and Secondary Social Media Source Identification [PDF]

open access: yesarXiv, 2021
Social networks like Facebook and WhatsApp have enabled users to share images with other users around the world. Along with this has come the rapid spread of misinformation. One step towards verifying the authenticity of an image is understanding its origin, including it distribution history through social media.
arxiv  

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Inference on the History of a Randomly Growing Tree [PDF]

open access: yesarXiv, 2020
The spread of infectious disease in a human community or the proliferation of fake news on social media can be modeled as a randomly growing tree-shaped graph. The history of the random growth process is often unobserved but contains important information such as the source of the infection.
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Quantifying Mental Health from Social Media with Neural User Embeddings [PDF]

open access: yesarXiv, 2017
Mental illnesses adversely affect a significant proportion of the population worldwide. However, the methods traditionally used for estimating and characterizing the prevalence of mental health conditions are time-consuming and expensive. Consequently, best-available estimates concerning the prevalence of mental health conditions are often years out of
arxiv  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Natural selection. VII. History and interpretation of kin selection theory [PDF]

open access: yes, 2013
Kin selection theory is a kind of causal analysis. The initial form of kin selection ascribed cause to costs, benefits, and genetic relatedness. The theory then slowly developed a deeper and more sophisticated approach to partitioning the causes of social evolution. Controversy followed because causal analysis inevitably attracts opposing views.
arxiv   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

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