Results 51 to 60 of about 1,519,351 (300)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
BMC Public Health, 2016 Background Despite the importance of adequate, un-crowded housing as a prerequisite for good health, few large cohort studies have explored the health effects of housing conditions. The Social Housing Outcomes Worth (SHOW) Study was established to assess
Michael G. Baker +5 more
doaj +1 more source
Parameters for improvement of the housing quality in social housing dwellings [PDF]
Facta Universitatis. Series: Architecture and Civil Engineering, 2014 Experiences of the countries with developed social housing sector indicate that the role of social housing should not be treated in a limited manner, considered to be just a roof over one’s head, whereby housing quality will be neglected ...
Petković-Grozdanović Nataša +3 more
doaj +1 more source
More Social Housing? A Critical Analysis on Social Housing Provision in Spain
Critical Housing Analysis, 2017 Since the 1950s Spain has developed a set of policies aimed at stimulating ownership through subsidies mainly in the form of interest rates or mortgage quotas to developers and households neglecting other forms of housing provision, for instance social rent.
Pareja Eastaway, Montserrat +1 more
openaire +2 more sources
The promised territories: the production of branded housing projects in contemporary Turkey [PDF]
, 2016 Cities in Turkey, following the neoliberal restructuring of the country, have undergone a process of transformation in the last decade at a greater pace than experienced in previous periods.
Serin, Bilge
core +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Belgeo, 2023 While the retreat of state from social housing sector has been a mainstream trend worldwide in the past decades under neoliberalism, the Chinese government returned to its role of social housing provision since the year 2007. This triggers an interesting
Danyang Li
doaj +1 more source
Social housing and digital exclusion [PDF]
, 2009 This report by the National Housing Federation Futures Project analyses the concept of digital exclusion, its effects, the role of housing associations in tackling its consequences and possible interventions that may ...
Winchester, Nik
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source