Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Performance feedback and middle managers’ divergent strategic behavior: The roles of social comparisons and organizational identification [PDF]
Murat Tarakci +4 more
openalex +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Community identification, social support, and loneliness: The benefits of social identification for personal well-being. [PDF]
McNamara N +8 more
europepmc +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Correction: Identification and Induction of Human, Social, and Cultural Capitals through an Experimental Approach to Stormwater Management, Sustainability 2012, 4, 1669-1682 [PDF]
Olivia Odom Green +4 more
openalex +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Two studies dealing with the community quality of MUDs (Multi User Domains/Dungeons)—a special group of multiplayer-online-games—are reviewed. The first study focuses on the social identification of the MUD players with their respective MUDs and presents
Nicola Döring
doaj
A Uniform for Narrating the Nurse in the Wheel of Time: An Interpretative Phenomenological Study
Aim To explore the symbolic and functional value that nurses attribute to their uniforms and profession. Design An interpretative phenomenological study.
Jacopo Fiorini +4 more
doaj +1 more source

