Results 91 to 100 of about 737,776 (266)

The disorientation of experience in the Information Society

Revista CIDOB d'Afers Internacionals, 2011
This article introduces a new cultural study based on the interpretation of certain principles of social complexity theory. We analyse the impact of the Information Society on the construction of European cultural identities.
Fernando R. Contreras
doaj  

Secrets of More Likes: Understanding eWOM Popularity in Wine Tourism Reviews Through Text Complexity and Personal Disclosure

Tourism and Hospitality
Online reviews increasingly shape experiential travel decisions. This study investigates how structural and linguistic features of user-generated content influence peer endorsement in wine tourism.
Jie Zheng, Xi Wang, Yaning Mao
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Relational aesthetics: A duoethnographic research on feminism

European Journal for Research on the Education and Learning of Adults, 2019
This paper offers a frame to reflect on the role of aesthetics in the development of a critical pedagogy for social justice in adult education. Arts-based research and practice have the power to illuminate the participants' views, ideas, and feelings, as
Laura Formenti, Silvia Luraschi, Gaia Del Negro   +2 more
doaj   +1 more source

Indigenous Theologies in Indonesia: Syncretism, State Recognition, and the Resilience of Aliran Kepercayaan [PDF]

Pharos Journal of Theology
This article provides a thorough examination of indigenous theology in Indonesia by focusing on the following six belief systems: Kejawen, Sunda Wiwitan, Kaharingan, Marapu, Ada’ Mappurondo, and Parmalim.
Cindy Vebyola Batubara, Alwi Dahlan Ritonga, Sakti Ritonga   +2 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The influence of fine art photography on the perception of social issues: analysis of works on emigration and identity

Clío
The study explored the visual impact of Fine Art photography on public perceptions of social issues, focusing on migration and identity. Using an interdisciplinary approach, the research combined visual studies, semiotics, iconography, and social theory.
Anastasiia Terentieva
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Modelling complexity of gender as an agent of change [PDF]

, 2006
Social inclusion continues to develop as a key issue in responsible design practices. To date, we have witnessed change in the development of inclusivity for the aged, and the physically and mentally challenged, but little more than exploration by ...
Hilton, Kevin
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source