Results 81 to 90 of about 39,434 (269)

The disorientation of experience in the Information Society

Revista CIDOB d'Afers Internacionals, 2011
This article introduces a new cultural study based on the interpretation of certain principles of social complexity theory. We analyse the impact of the Information Society on the construction of European cultural identities.
Fernando R. Contreras
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Being an identity prop: some ethical implications

, 2009
During recent fieldwork in Namibia I noticed that the people I worked with often took care to arrange our public encounters so that onlookers did not interpret our relationship in ways that might be inconvenient.
Busher, Joel
core  

Secrets of More Likes: Understanding eWOM Popularity in Wine Tourism Reviews Through Text Complexity and Personal Disclosure

Tourism and Hospitality
Online reviews increasingly shape experiential travel decisions. This study investigates how structural and linguistic features of user-generated content influence peer endorsement in wine tourism.
Jie Zheng, Xi Wang, Yaning Mao
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Complexity and communities: The application of complexity to community studies

, 2015
Understanding community dynamics has always been a challenge for policy-makers. Often community policy has been ineffective and wasteful. This research explores and sets out an alternative, complexity-informed approach to community studies.
Large, David
core  

Almost a proper Buddhist : the post-secular complexity of heritage Buddhist teen identity in Britain [PDF]

, 2014
This qualitative study explores how Buddhist affiliation relates to practice, how Buddhist teens define and experience their religious identity and which sociological paradigms are helpful in understanding the dynamics of Buddhist teen identity.
Thanissaro, Phra Nicholas, Phra Nicholas Thanissaro   +1 more
core   +1 more source

Relational aesthetics: A duoethnographic research on feminism

European Journal for Research on the Education and Learning of Adults, 2019
This paper offers a frame to reflect on the role of aesthetics in the development of a critical pedagogy for social justice in adult education. Arts-based research and practice have the power to illuminate the participants' views, ideas, and feelings, as
Laura Formenti, Silvia Luraschi, Gaia Del Negro   +2 more
doaj   +1 more source

Indigenous Theologies in Indonesia: Syncretism, State Recognition, and the Resilience of Aliran Kepercayaan [PDF]

Pharos Journal of Theology
This article provides a thorough examination of indigenous theology in Indonesia by focusing on the following six belief systems: Kejawen, Sunda Wiwitan, Kaharingan, Marapu, Ada’ Mappurondo, and Parmalim.
Cindy Vebyola Batubara, Alwi Dahlan Ritonga, Sakti Ritonga   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source