Results 81 to 90 of about 36,163 (224)

Social Identity Complexity: Theories, Methods and Advances

open access: yesAdvances in Psychological Science, 2013
Su-Fei XIN, Zi-Qiang XIN
openaire   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

The Evolution of Intelligence from Active Matter to Complex Intelligent Systems via Agent-Based Autopoiesis

open access: yesProceedings
Intelligence is a central topic in computing and philosophy, yet its origins and biological roots remain poorly understood. The framework proposed in this paper approaches intelligence as the complexification of agency across multiple levels of ...
Gordana Dodig-Crnkovic
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

CHARACTER ANALYSIS THROUGH DIALOGUE IN ENOLA HOLMES (2020): A STUDY USING M.H ABRAM’S THEORY

open access: yesLanguage Literacy: Journal of Linguistics, Literature, and Language Teaching
This study examines the characterization of the film Enola Holmes (2020), focusing on the emotional, intellectual, and moral aspects of the characters as revealed through dialogue.
Tyas Putri Aistyana, Yeny Prastiwi
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Tools for assessing professional identity in health professions education: A scoping review

open access: yesJournal of Medical Ethics and History of Medicine
Due to the complexity and multidimensional nature of professional identity assessment in health professions education, it is essential to establish appropriate criteria.
Zahra Sadat Tabatabaei   +2 more
doaj  

Identity Framing as Resilience in Selected Nicknames of Nigerian Street Children

open access: yesLanguages
Street children who are forced onto the streets due to oppressive experiences use a variety of strategies, including nicknaming, to cope with street adversities.
Ezekiel Opeyemi Olajimbiti
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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