Results 61 to 70 of about 18,309,719 (259)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Challenging Ajeg Bali: Subaltern Protestant Identity and Cultural Politics under Dutch Rule in 1930s [PDF]

open access: yesSHS Web of Conferences
This study investigates the social, political, and cultural dynamics of the Balinese Protestant community in Untal-Untal, Badung, during the 1930s, following missionary activities led by Tsang To Hang.
Hendra Mas Martayana I Putu   +6 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Complexity, Governance and Networks: Introduction to the Inaugural Issue

open access: yes, 2014
From the introduction: 1. Yet Another Journal? Why is it necessary to publish a new journal about complexity, governance, and networks? There has been an increasing interest in complexity, governance, and network studies in recent decades.
Morçöl, Göktuğ   +2 more
core   +1 more source

‘Are You Greater than Our Ancestors?’ Reading John 4:1–42 with the Lens of Social Identity Complexity in the Context of Ethno-Religious Solidarity, Conflict and Peacebuilding

open access: yesReligions
This paper studies the encounter between Jesus and the Samaritan woman in John 4:1–42 through the lens of Social Identity Complexity (SIC) theory, focusing on its implications for ethno-religious solidarity, conflict resolution and peacebuilding in ...
Dogara Ishaya Manomi
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Social Identity Strategies in Recent Economics [PDF]

open access: yes
This paper reviews three distinct strategies in recent economics for using the concept of social identity in the explanation of individual behavior: Akerlof and Kranton’s neoclassical approach, Sen’s commitment approach, and Kirman et al.’s complexity ...
John B Davis
core  

Thinking identity with difference: Society and theory [PDF]

open access: yes, 2017
The first part of the article notes the sudden and conspicuous interest for the problem of identity at the turn of the 21st century. It presents Modern and postmodern conceptualizations of collective identity of social theorists.
Krstić Predrag   +2 more
core   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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