Results 61 to 70 of about 39,434 (269)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Complexity, theory and praxis: researching collaborative learning and tutoring processes in a networked learning community [PDF]
, 2003 This paper explores the complexity of researching networked learning and tutoring on two levels. Firstly, on the theoretical level, we argue that the nature of praxis in networked environments (that is, learning and tutoring) is so complex that no ...
De Laat, M. +5 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
YoungThis article explores young people’s emotional associations with activism in relation to their social identity, sense of agency and activist participation.
Silvia Behrens
doaj +1 more source
Relational identity and principle of solidarity as the bases for the intercultural education
Teoría de la Educación: Revista Interuniversitaria, 2014 Having established the failure of multiculturalism and all theoretical and practical alternatives for the study, analysis and management of social diversity and complexity, emerges the need to raise multiculturalism as the only logical alternative for ...
Nuria GARRO GIL, Sarah CARRICA OCHOA
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Superdiversity and social complexity
, 2021 Based on a keynote lecture1, this paper places the superdiversity concept in relation tocertain ideas surrounding complexity theory. Further, the implications of superdiversityfor social stratification processes are stressed. Finally, with a view towards
Vertovec, S. ; https://orcid.org/
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Exploring the Complexity of Identities and Boundaries within the New Testament World
The objective of this Special Edition is to engage in a critical examination of the intricate nature of identity as depicted in the New Testament and the related literature, particularly through the lens of social identity complexity theory ...
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Unfolding the layers of LGBTQ+ identity, resilience, and multicultural perspectives in Vietnam
Frontiers in SociologyMy personal narrative, intertwined with the theoretical acumen of Queer Theory and intersectionality framework, is used within this article as one way of underlining the critical role of lived experiences in forming an insight into LGBTQ+ identity and ...
Huy Lam-Nguyen
doaj +1 more source