Results 41 to 50 of about 39,434 (269)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Exploring relationships between self-identity complexity, other-identity complexity, and multicultural counseling competence in counselors [PDF]
, 2013 As society grows more diverse, future counselors will be seeing clients with complex concerns around issues of identity, belonging, and acceptance. In order to effectively serve the United States population, it is imperative to provide future counselors ...
NC DOCKS at The University of North Carolina at Greensboro +1 more
core
Task complexity and social identity interact to shape interpersonal coordination in rugby union
Acta PsychologicaGrounded in an ecological dynamics framework and drawing on social identity theory, this experimental study examined how task complexity (manipulated by the defenders' initial positions) and attackers' motivational goals (either self- or team-oriented ...
Quentin Bourgeais +4 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
International Journal of Educational Research OpenThis study investigates the multifaceted impacts of parental gambling on children across educational, cultural, sociological, psychological, and economic dimensions.
Ömer Gökhan Ulum
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Problematyka (nie)męskości w procesie psychoterapii
InterAlia, 2015 The author tries to demonstrate the relations between sociological concepts of constructing men’s gender identity and the theory and practice of psychoanalytic psychotherapy.
Mateusz Kobryn
doaj +1 more source
Challenging Ajeg Bali: Subaltern Protestant Identity and Cultural Politics under Dutch Rule in 1930s [PDF]
SHS Web of ConferencesThis study investigates the social, political, and cultural dynamics of the Balinese Protestant community in Untal-Untal, Badung, during the 1930s, following missionary activities led by Tsang To Hang.
Hendra Mas Martayana I Putu +6 more
doaj +1 more source