Results 111 to 120 of about 737,776 (266)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Attempts to Precisely Clarify the Object of Political Science Research in Publications by Polish Political Scientists

open access: yesTeoria Polityki
The article attempts to analyze the achievements of Polish political theorists concerning the subject of political science research, its complexity and evolution, from the 70s of the 20th century to ...
Magdalena Mikołajczyk
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Evolution of Intelligence from Active Matter to Complex Intelligent Systems via Agent-Based Autopoiesis

open access: yesProceedings
Intelligence is a central topic in computing and philosophy, yet its origins and biological roots remain poorly understood. The framework proposed in this paper approaches intelligence as the complexification of agency across multiple levels of ...
Gordana Dodig-Crnkovic
doaj   +1 more source

Social Identity Complexity: Theories, Methods and Advances

open access: yesAdvances in Psychological Science, 2013
Su-Fei XIN, Zi-Qiang XIN
openaire   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

CHARACTER ANALYSIS THROUGH DIALOGUE IN ENOLA HOLMES (2020): A STUDY USING M.H ABRAM’S THEORY

open access: yesLanguage Literacy: Journal of Linguistics, Literature, and Language Teaching
This study examines the characterization of the film Enola Holmes (2020), focusing on the emotional, intellectual, and moral aspects of the characters as revealed through dialogue.
Tyas Putri Aistyana, Yeny Prastiwi
doaj   +1 more source

The Scientist-Practitioner in a Counselling Psychology Setting [PDF]

open access: yes, 2006
The human psyche is influenced by an extraordinary complexity of experiences. Many would therefore maintain that we can never completely understand another human being.
Bury, D., Strauss, S. M.
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy