Results 111 to 120 of about 17,268,978 (250)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Journal of Theoretical and Applied Electronic Commerce ResearchThis study examines how followers’ social identity dimensions—cognitive, evaluative, and affective—affect their purchase intention for fashion products promoted by Instagram influencers.
Ghaith Al-Abdallah +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Transformation of Social Identity Among Former Thugs in Surakarta City
Jurnal Sosiologi AgamaThis article examines the transformation of the social identity of former gangsters (preman) in the city of Solo who seek to rebuild their religious identity through the process of hijrah and active participation in religious communities such as Juba ...
Warsito
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
This Is Who I Am: The Selfie as a Personal and Social Identity Marker
International Journal of Communication, 2019 Prior studies have described selfies as narcissistic vehicles of self-presentation; by contrast, based on social identity theory, this survey of young adults (N = 472) examined how selfies signify forms of personal and social identity.
Valerie Barker, Nathian S. Rodriguez
doaj
Frontiers in PsychologyPurposeThis study focuses on the obstacles to the transformation of green consumption intention into behavior, explores the interaction between information framing (positive and negative) and behavioral agency types (individual and group), and reveals ...
Zhenzhen Peng, Ziduo Su, Mingfang Dong
doaj +1 more source
, 2017 Moral norms and values are key features of human essence, that provide the standards against which behavior is evaluated. Some moral norms and values are universally endorsed (e.g., “do no harm”), others can be more specific (e.g., “eat no meat ...
Ellemers, N., Naomi Ellemers
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source