Results 111 to 120 of about 177,397 (293)

Culture and the study of social identity

open access: yes, 2010
By declaring the social to be universal and timeless the formalised study of social identity – drawn mostly from sociology, social policy, social psychology, and cultural studies – ignores the fact that as a discrete domain the social has a definite a ...
Wickham, G.
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

State institutions and social identity: national representation in soldiers' and civilians' interview talk concerning military service

open access: yes, 2009
Theory and research deriving from social identity or self-categorization perspectives often starts out with the presumption that social actors necessarily view societal objects such as nations or states as human categories.
Susan Condor   +4 more
core   +1 more source

A socio-legal analysis of collective identity construction in social movements

open access: yesSortuz, 2015
This paper aims to analyze the processes of identity formation comprised within social movement actions. The case of the 8-N movement occurred in 2012 in Argentina is used as a central example of a collective identity formation through the use of new ...
Lucia Irene Lapenta
doaj  

Language and Identity in Ketepik Bulian Padi Played in Gambus Belitung: A Sociolinguistic Study

open access: yesSociety
Gambus and song lyrics complement each other, creating harmony while representing the history and cultural identity of their communities. This study aims to explore identity through diction choices, phonological processes, and musical notes in Gambus ...
Aimie Sulaiman   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Social networks of British-Bangladeshi young women [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy by Akter Sina (also known as Sina Akter) and awarded by Brunel University.This research is about the Social Networks and Social Capital of British-Bangladeshi Young Women in relation to ...
Sina Akter, Akter, Sina
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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