Results 101 to 110 of about 2,882,964 (323)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Right-Wing Populism, Social Identity Theory, and Resistance to Public Health Measures During the COVID-19 Pandemic. [PDF]

Int J Public Health, 2022
Magnus KD.
europepmc   +1 more source

The Theory of Relational Cohesion: Review of a Research Program [PDF]

, 2002
In this paper we analyze and review the theory of relational cohesion and attendant program of research. Since the early 1990s, the theory has evolved to answer a number of basic questions regarding cohesion and commitment in social exchange relations ...
Lawler, Edward J, Thye, Shane R, Yoon, Jeongkoo   +2 more
core   +1 more source

Predicting participation in group parenting education in an Australian sample: The role of attitudes, norms, and control factors [PDF]

, 2009
We examined the theory of planned behavior (TPB) in predicting intentions to participate in group parenting education. One hundred and seventy-six parents (138 mothers and 38 fathers) with a child under 12 years completed TPB items assessing attitude ...
AP Kaiser, C Armitage, C Armitage, C Smith, D Dinkmeyer, D Johnson, DJ Terry, DJ Terry, F Frankel, H Einzig, H Tajfel, HW Goddard, I Ajzen, I Ajzen, J Barlow, J Barlow, JC Turner, JE Dumas, K McCurdy, K McCurdy, Katherine M. White, KL Johnston, KM White, KM White, KP Haggerty, Larne Wellington, LJ Cronbach, M Conner, M Fishbein, MH Becker, MR Sanders, MR Sanders, MR Sanders, P Sparks, P Sparks, R Spoth, R Spoth, R Spoth, R Spoth, S Stryker, S Stryker, S Stryker, T Gordon, T Perrino   +43 more
core   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Reviewing Identity in Postmodern Fiction: Modern Psychology vs. Psychoanalysis

Akofena
: This article reviews the theme of identity in postmodern literature through a comparison of psychoanalytical perspectives with modern psychological theories.
Hadda SLIMANI
doaj   +1 more source

Social Identity Theory for Investigating Islamic Extremism in the Diaspora

Journal of Strategic Security, 2013
An overview of literature on radicalization in the Muslim diaspora in Europe finds identity crises to be a key precipitant to the process. Studies also typically focus on the manipulation of identify by violent Islamic extremist groups.
Dina Al Raffie
doaj   +1 more source

A study of team cohesion and player satisfaction in two face-to-face games [PDF]

, 2013
In this paper we investigate the link between game rules, team cohesion and players’ satisfaction with their teams within face-to-face team-based games. To measure team cohesion, rules from two games were analysed from the perspective of Social Identity ...
Good, Judith, Martin, Eleanor
core  

Psycho-social factors influencing forest conservation intentions on the agricultural frontier [PDF]

, 2013
Remnant forest fragments are critical to conserve biological diversity yet these are lost rapidly in areas under agricultural expansion. Conservation planning and policy require a deeper understanding of the psycho-social factors influencing landholders’
Ajzen, Ajzen, Altrichter, Angelsen, Armitage, Bamberg, Bamberg, Beedell, Burnham, Burton, Byrne, Fielding, García-López, Gardner, Graham, Karppinen, Lambin, Lambin, Lokhorst, Lynne, Mastrangelo, Meyfroidt, Minato, Ostrom, Primmer, Roy Chowdhury, Schumacker, Schwartz, Seghezzo, Snoo, Snoo, St John, Stern, Stobbelaar, Stryker, Vaske, Wall, Wauters   +37 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source