Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Reviewing Identity in Postmodern Fiction: Modern Psychology vs. Psychoanalysis
: This article reviews the theme of identity in postmodern literature through a comparison of psychoanalytical perspectives with modern psychological theories.
Hadda SLIMANI
doaj +1 more source
Old age identity in social welfare practice
The main objective of this study was to examine the process of old age identity construction within a setting of social welfare work with old people. We sought to identify social welfare practices that construct and enforce certain old age identities ...
Wilinska, Monika +5 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Modern discrimination: How perperators and targets interactively perpetuate social disadvantage [PDF]
Stereotypes and discriminatory behavior do not necessarily imply that people are explicitly devalued or actively excluded from attractive positions in society.
Barreto, M +5 more
core +2 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Social Identity Theory for Investigating Islamic Extremism in the Diaspora
An overview of literature on radicalization in the Muslim diaspora in Europe finds identity crises to be a key precipitant to the process. Studies also typically focus on the manipulation of identify by violent Islamic extremist groups.
Dina Al Raffie
doaj +1 more source
Right-Wing Populism, Social Identity Theory, and Resistance to Public Health Measures During the COVID-19 Pandemic. [PDF]
Magnus KD.
europepmc +1 more source
Identity Status, Gender, and Social Comparison Among Young Adults
The aim of this study was to investigate identity status globally and across identity domains among young Swedish adult women and men. Also, potential differences in social comparison among identity statuses were evaluated.
Frisén, Ann, +3 more
core +1 more source

