An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Reviewing Identity in Postmodern Fiction: Modern Psychology vs. Psychoanalysis
: This article reviews the theme of identity in postmodern literature through a comparison of psychoanalytical perspectives with modern psychological theories.
Hadda SLIMANI
doaj +1 more source
Immigrants in Iranian Society: An Identity Perspective Based on Breakwell's Identity Process Theory (Case Study: Brick Kilns of Mahmoudabad, Tehran) [PDF]
IntroductionIdentity encompasses the array of characteristics, through which individuals define themselves and are recognized by others, forming a dynamic construct shaped by social interactions and historical memory.
Behnoosh Taherkhani +3 more
doaj +1 more source
Fostering Hotel-Employee Creativity Through Micro-Level Corporate Social Responsibility: A Social Identity Theory Perspective. [PDF]
Ahmad N +5 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Social Identity Theory for Investigating Islamic Extremism in the Diaspora
An overview of literature on radicalization in the Muslim diaspora in Europe finds identity crises to be a key precipitant to the process. Studies also typically focus on the manipulation of identify by violent Islamic extremist groups.
Dina Al Raffie
doaj +1 more source
Understanding Camouflaging as a Response to Autism-Related Stigma: A Social Identity Theory Approach. [PDF]
Perry E, Mandy W, Hull L, Cage E.
europepmc +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source

