Results 121 to 130 of about 7,079,688 (312)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The Impact of Equity Engagement Evaluating the Impact of Shareholder Engagement in Public Equity Investing [PDF]
, 2014 Over the last decade, growing numbers of investors have become increasingly concerned with the environmental and social impact of their investments across asset classes.
Becky Johnson +4 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Exploring New Barriers to the Implementation of Frugal Innovation Projects Among Spanish Ngdos
Quaestiones GeographicaeThe concept of frugal innovation has attracted significant academic interest over the last decade, but its diffusion among non-governmental organisations (NGOs) with technology transfer programmes in the Global South has been insufficiently examined ...
Rodríguez Beatriz Delfa +2 more
doaj +1 more source
, 2016 This thesis investigates how social purpose organisations collect and communicate information on their social impact through social impact accounting . It seeks to understand how different logics shape the current practice of social impact accounting, and how this practice may be shaped by social investment and standardisation.
openaire +2 more sources
Do Impact Investments Contribute to Portfolio Performance? A Preliminary Investigation [PDF]
, 2017 Social Impact Investments (SII) intentionally aims at generating social impact and financial return. Portfolio diversification is one of the under-investigated areas in SII literature.
Chaippini, Helen +2 more
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Health EquityPurpose: There is a Black maternal health crisis in America, with significant racial disparities in birth outcomes for Black women in Washington, DC. Programs designed to reduce these inequities must intentionally address the role of systemic racism and ...
Erin Snowden +4 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Social Impact of Renewable Energy Sources in the Province of Loja [PDF]
, 2018 In the future energy development of the planet, renewable energies are decisive, because of the benefits that these entail in their use, besides being inexhaustible; These are used in different ways, in heating in electrical energy, electrochemistry ...
Chilán, J. C. (Julio) +5 more
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