Results 171 to 180 of about 1,025,463 (296)

Bridging the gap between sports/physical activity and prevention of non-communicable diseases through a human rights based approach

Annals of Global Health, 2016
K. Koutsioumpas
doaj   +1 more source

Leisure involvement, social inclusion, and happiness in Türkiye: a mediational analysis. [PDF]

Front Public Health
Budak D, Yumuk ED.
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Public administration in contested societies

Administration, 2016
McMahon Denis
doaj   +1 more source

What can complex systems theory reveal about social inclusion. [PDF]

World Psychiatry
Speyer H.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Advancing social inclusion for people with co-occurring mental health and substance use disorders. [PDF]

World Psychiatry
Smelson D.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Dismantling structural violence to enable structural transformation and consequently social inclusion. [PDF]

World Psychiatry
Jones N.
europepmc   +1 more source

Center for Social Equity + Inclusion Action Plan

, 2017
Art and design have far-reaching capacities for generating shared language and connecting people and communities. The creative forms we study at RISD are powerful means for conveying ideas and shaping experiences across habituated boundaries.
Payne, Rene Watkins, Somerson, Rosanne, Center for Social Equity & Inclusion,   +2 more
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