Results 81 to 90 of about 13,496,740 (294)
The Observatory on Gender-Based Violence in Bizkaia (OVGB): An Experience of Good Practices
Sortuz, 2017 The Observatory on Gender-based Violence in Bizkaia (OVGB) emerged as an initiative of the Bizkaia Provincial Council (DFB) in 2003. It began to operate in 2004.
Berta Díaz Arbesú
doaj
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
E-government and the Electronic Transformation of Modes of Rule: The Case of Partnerships [PDF]
Journal of Systemics, Cybernetics and Informatics, 2004 This paper critically examines some aspects of the discursive and material transformation of government as a result the deployment of the internet and new information technologies.
Paul Henman
doaj
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Like a Social Breath: Homecare’s Contributions to Social Inclusion and Connectedness of Older Adults. [PDF]
, 2022 The detrimental effects of social isolation on health and well-being bring forward the need for increasing social inclusion and connectedness for older, homebound adults. Homecare services may be a source of social inclusion, but the inclusive dimensions
Skatvedt, Astrid Helene +2 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
National action plan against poverty and social exclusion 2003–2005
, 2003 This National Action Plan Against Poverty and Social Exclusion is a product of the policies agreed and being developed under social partnership and also takes account of the wider consultative process. It is now envisaged that the strategic planning
Office for Social Inclusion
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Gaming motivation and well-being among Norwegian adult gamers: the role of gender and disability
Frontiers in Medical TechnologyIntroductionDigital gaming is a popular and often social activity, also among adults. However, we need more knowledge of the social dynamics of gaming and its potential benefits for one's well-being.
Beate W. Hygen +6 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source