Results 41 to 50 of about 1,062,305 (293)

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Transitional Domesticity: Collectivisation and Fractionalisation in Peer-to-Peer Digital Citizenry Learning from Socio-Innovations of Chinese-Asian Historical Contexts

Open Philosophy, 2023
Collectivisation, as a socio-innovation, is an incremental part of history that has much to teach on questions of asset commoning. Such notions can provide renewed perspectives in understanding today’s peer-to-peer (p2p) economy and its influence on ...
Ng Provides
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

“It isn't because they don't love their children”: social norms shaping young fathers' caregiving in Uganda

Frontiers in Sociology
This study investigates the influence of social norms on male caregiving in Uganda and considers the implications for tailoring and scaling the REAL Fathers mentoring program across six regions. By identifying key norms and reference groups, the findings
Aloysious Nnyombi, Aloysious Nnyombi, Aloysious Nnyombi, Ramadhan Kirunda, Anslem Wandega, Moses Komagum, Deogratias Yiga, Kathryn M. Barker, Rebecka Lundgren   +8 more
doaj   +1 more source

Scaling New Heights: How to Spot Small Successes in the Public Sector and Make Them Big [PDF]

, 2010
Examines barriers to bringing innovations to scale in the social sector and recommends developing a market for social outcomes, designing funding models that encourage scaling, shaping the field of knowledge about what works, and investing in ...
Geoff Mulgan, Jitinder Kohli
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Social Responsibility of Business: Strategy and Innovations

Vestnik MGIMO-Universiteta, 2014
In this article social practicians of large Russian corporations, conditions of creation of social strategy by them are analyzed. The ambiguous treatment of the corporate social responsibility (CSR) of subjects of interaction in system "business-society ...
G. N. Illina
doaj   +3 more sources

Social Innovations Patents.

Journal of Social Work Education and Practice, 2023
The core of this paper is focused on establishing a Social Innovation Patent System for the coding, evaluation, certification and scaling-up social innovations. The system is framed under the Open Social Innovation framework.
Javier Spila, David González
doaj   +2 more sources

Subcultural and social innovations in the campaign for nuclear disarmament [PDF]

, 2004
In times of war and rumours of peace, when ‘terrorism’ and ‘torture’ are being revisited and redefined, one of the things some of us should be doing is talking and writing about cultures of peace.
McKay, GA
core