Results 41 to 50 of about 1,058,751 (293)

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou   +10 more
wiley   +1 more source

Modelling diffusion of innovations in a social network [PDF]

open access: yes, 2002
A new simple model of diffusion of innovations in a social network with upgrading costs is introduced. Agents are characterized by a single real variable, their technological level.
A. Arenas   +12 more
core   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

“It isn't because they don't love their children”: social norms shaping young fathers' caregiving in Uganda

open access: yesFrontiers in Sociology
This study investigates the influence of social norms on male caregiving in Uganda and considers the implications for tailoring and scaling the REAL Fathers mentoring program across six regions. By identifying key norms and reference groups, the findings
Aloysious Nnyombi   +8 more
doaj   +1 more source

Scaling New Heights: How to Spot Small Successes in the Public Sector and Make Them Big [PDF]

open access: yes, 2010
Examines barriers to bringing innovations to scale in the social sector and recommends developing a market for social outcomes, designing funding models that encourage scaling, shaping the field of knowledge about what works, and investing in ...
Geoff Mulgan, Jitinder Kohli
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Transitional Domesticity: Collectivisation and Fractionalisation in Peer-to-Peer Digital Citizenry Learning from Socio-Innovations of Chinese-Asian Historical Contexts

open access: yesOpen Philosophy, 2023
Collectivisation, as a socio-innovation, is an incremental part of history that has much to teach on questions of asset commoning. Such notions can provide renewed perspectives in understanding today’s peer-to-peer (p2p) economy and its influence on ...
Ng Provides
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Rendering Affective Atmospheres: The Visual Construction of Spatial Knowledge About Urban Development Projects

open access: yesUrban Planning, 2022
Renderings are digital visualisations of urban development projects in the field of urban design that aim to create spatial knowledge about future-built urban environments, which we also refer to as imaginaries.
Sophie Mélix, Gabriela Christmann
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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