Results 121 to 130 of about 870,885 (308)

Institute on Community Integration Annual Report: 1995-96

open access: yes, 1996
The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Affiliated Program on Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Integration without Membership: Switzerland's Bilateral Agreements with the EU. CEPS Paperbacks. March 2006 [PDF]

open access: yes, 2006
Surrounded by European Union member states on all sides, Switzerland is one of the great anomalies of European integration. Although it is one of very few countries in Western Europe that has chosen to remain outside the EU, Switzerland is closely ...
Grolimund, Nina, Vahl, Marius
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Institute on Community Integration Annual Report: 1989-90

open access: yes, 1990
Note on language: In earlier RISP products, we used the word "retardation" to refer to IDD. Historically, this was common language in the profession and broader society. Because of its broad and common use, outdated language may also appear in other RISP
Institute on Community Integration
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Social Ecological Model Analysis for ICT Integration

open access: yes, 2013
ICT integration of teacher preparation programmes was undertaken by the Australian Teaching Teachers for the Future (TTF) project in all 39 Australian teacher education institutions and highlighted the need for guidelines to inform systemic ICT ...
Zagami, J
core  

‘Integration’ as a Process of Inclusion for Migrants? The Case of Long-Term Residents in the EU. CEPS Working Documents No. 219, 1 March 2005 [PDF]

open access: yes, 2005
At a time when the development of a common EU immigration policy remains far from a reality, the integration of migrants has been placed at the very top of the EU agenda.
Carrera, Sergio
core  

Aim and Duty; Sword and Shield: Analysing the Cause and Effects of the Malleability of 'Social Integration' in EU Law

open access: yes, 2018
: Social integration is often depicted as a means of enhancing the Union’s legitimacy. Most recently, a reinvigorated “social Europe” has been back on the agenda following the United Kingdom’s Brexit vote.
Reynolds, S
core   +1 more source

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