Results 131 to 140 of about 1,115,651 (315)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The importance of hair in human perception of electric fields – A double-blind repeated measures study

Scientific Reports
Electric fields (EFs) are an integral part of modern life which might affect humans in terms of conscious perception. Despite their ubiquity, the mechanisms underlying EF perception remain underexplored.
Kathrin Jankowiak, Andrea Kaifie, Julia Krabbe, Maike F. Dohrn, Simon Kimpeler, Frederik Mingers, Ralph Kühn, Thomas Kraus, Michael Kursawe   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Social Touch in Human–Robot Interaction

In this book for researchers and students, editors Shiomi and Sumioka bring together contributions from researchers working on the CREST project at ATR Deep Interaction Laboratories, a world leader in social robotics, to comprehensively describe robot ...

core   +1 more source

Personality intervention affects emotional stability and extraversion similarly in older and younger adults

Communications Psychology
Past research showed that personality traits develop less strongly after younger adulthood, though the underlying processes remain poorly understood, and personality intervention studies scarcely investigated age differences.
Gabriela Küchler, Kira S. A. Borgdorf, Corina Aguilar-Raab, Wiebke Bleidorn, Jenny Wagner, Cornelia Wrzus   +5 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Evaluating social & ubiquitous human-robot interaction

, 2010
Presented at the 7th International Conference on Ubiquitous Robots and Ambient Intelligence (URAI 2010), Busan, Korea, 24th-27th November, 2010While many robotic initiatives now share the thesis that robots are a compelling instance of those artefacts ...
Sassu, Antonella, O'Hare, G. M. P. (Greg M. P.), Holz, Thomas, Dragone, Mauro, O\u27Hare, G. M. P. (Greg M. P.)   +4 more
core  

Material Constraints for Assistant-Supported Learning

Social Interaction
This paper explores classroom desk interaction where the student has a visual impairment (VIS), and the interaction involves a third supportive party, the student’s learning support assistant.
Thomas L. W. Toft, Brian L. Due
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

On Unplanned Educational Activities in the Preschool

Social Interaction
This article concerns a learning environment in a preschool which includes a preschool teacher and two bilingual children. The article details how an activity of counting is introduced in the course of packing up a game and increasingly turns into an ...
Elisabeth Muth Andersen, Catherine E. Brouwer, Elisabeth Dalby Kristiansen, Maja Sigurd Pilesjö   +3 more
doaj   +1 more source