Results 191 to 200 of about 3,834,889 (342)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Understanding and explaining differences across minds in social interaction: insights from social neuroscience and clinical psychiatry. [PDF]

Eur Arch Psychiatry Clin Neurosci
Kamp D, Bolis D, Schilbach L.
europepmc   +1 more source

A Retesting of the Validity of an Assessment Tool in Music Therapy for Measuring Social Interactions of Children with Disability

, 2016
양은아
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Impact of video game addiction on social interaction: An observational review examining loneliness, social anxiety, and social activity. [PDF]

World J Psychiatry
Byeon H.
europepmc   +1 more source

Developing the Competency of Future Physical Education Specialists in Professional Interaction in the Field of Social Communications

, 2020
Rymma Redchuk, Тетяна Дорошенко, Nataliia Havryliuk, Serhii Medynskii, Руслана Сойчук, Оксана Петренко, Роман Павелків, Petrо Rybalko, Nelia Maliar, Eduard Maliar, Myroslava Chornodon, Vitalii Boretskyi, Roman Pavelkiv, Rivne State University of the Humanities, Petro Rybalko, Sumy Makarenko State Pedagogical University, Nelia Maliar, Ternopil National Economic University, Eduard Maliar, Ternopil National Economic University, Myroslava Chornodon, Vasyl’ Stus Donetsk National University, Vitalii Boretskyi, Vasyl’ Stus Donetsk National University   +23 more
openalex   +2 more sources

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Impact of physical exercise on health and social interaction in older adults: a meta-analysis. [PDF]

Front Public Health
Tao M, Li S, Li L, Cao Y, Zhuang J.
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

The impact of online social interaction on college students' socio-emotional competence mediated by bonding social capital. [PDF]

Sci Rep
Xiong Y, Zhou Y.
europepmc   +1 more source