Results 181 to 190 of about 1,115,651 (315)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Research on the intervention of Mandala drawing therapy for social interaction disorders in children with autism. [PDF]

Front Psychiatry
Zhang L, Luo L, Xia Q, Li F.
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

The Anterior BNST Is Required for Novelty-Driven Social Interaction. [PDF]

J Neurosci
Jacobs JT, Aholt ML, Lineberry T, Adjei MP, Qasem E, Aaflaq S, Athul SW, Ellsworth BS, Nordman JC.   +8 more
europepmc   +1 more source

Astrocytes in predictive processing of emotion: Kir4.1 as precision modulator of social interaction. [PDF]

Acta Pharm Sin B
Basu A, Kaye AP.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Validation of socialbit as a smartwatch algorithm for social interaction detection in a clinical population. [PDF]

Sci Rep
Dhand A, Tate S, Mack C, Carozza S, Farynyk D, Bourahla M, Adeboye O, Cooke G, Berglund O, Dahima R, Luo M, Dhongade V, Usmanov GS, White K, Bernal AM, Zafonte R, Narayanan S, Lee M, Mehl MR, Shin M.   +19 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The social organisation of news interview interaction [PDF]

This thesis describes and analyses aspects of the social organisation of British news interview interaction. After a review of the sociological literature on the British news interview in Chapter 1, and a discussion of the evolution of news ...
Greatbatch, David
core  

SocialGen: Modeling Multi-Human Social Interaction with Language Models. [PDF]

Proc Int Conf 3D Vis
Yu H, Zhang J, Chen C, Xiang T, Fang Y, Niebles JC, Adeli E.   +6 more
europepmc   +1 more source