Results 61 to 70 of about 3,898,666 (292)

A Promising Practice: Using Facebook as a Communication and Social Networking Tool [PDF]

open access: yes, 2013
Individuals with autism often face barriers to social interaction. Residing in a rural environment can compound these difficulties for individuals diagnosed with autism.
Jacobs, Gloria   +2 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

"Third places" and social interaction in deprived neighbourhoods in Great Britain [PDF]

open access: yes, 2012
This paper explores social interaction in local ‘public’ social spaces such as local shops, pubs, cafés, and community centres in deprived neighbourhoods.
Hickman, Paul
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Interacting for the environment:Engaging Goffman in pro-environmental action [PDF]

open access: yes, 2016
Whilst there are profound disagreements about how more sustainable forms of living might be achieved, most research on pro-environmental action recognises it as a fundamentally social challenge – demanding shifts not merely in individuals’ attitudes and ...
(GAP) Global Action Plan   +11 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Sally and… Cozmo? Training theory of mind using a toy robot: a pilot study

open access: yesFrontiers in Psychology
IntroductionChildren with autism spectrum disorder (ASD) often show impairments in Theory of Mind (ToM). This pilot study examined whether a commercially available toy robot (Cozmo) could support false-belief training within an Applied Behavior Analysis (
Davide Ghiglino   +4 more
doaj   +1 more source

Exploratory Analysis of Pairwise Interactions in Online Social Networks [PDF]

open access: yes, 2017
In the last few decades sociologists were trying to explain human behaviour by analysing social networks, which requires access to data about interpersonal relationships.
Humski, Luka   +2 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy