Results 161 to 170 of about 431,994 (303)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Mitigating Social Isolation Among Peritoneal Dialysis Patients: The Impact of Educational Level, Physical Activity, and Familial Support

Huifang Cai,1,* Zongbi Wu,2,* Jieling Xu,1 Taifen Wang,2 Yanfeng Li,3 Youli Jiang,3 Mingming Xu2 1Guangzhou University of Chinese Medicine Fourth Clinical Medical College, Shenzhen, People’s Republic of China; 2Nursing Department, Shenzhen ...
Jiang Y, Wu Z, Li Y, Xu M, Wang T, Cai H, Xu J   +6 more
core  

Loneliness, Inhibition, and Friendlessness: Associations with Adolescents' Appearance-Related Concerns, Attractiveness, and Teasing about Appearance

, 2015
The aim of the present study was to identify which aspects relating to appearance-related concerns and social experiences, and status amongst peers, are relevant to understanding social isolation in early adolescents. In a sample 387 boys and girls (Mage
Zimmer-Gembeck, MJ, Webb, HJ, Ferguson, S   +2 more
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Loneliness and social isolation at the emergency department: a scoping review protocol. [PDF]

BMJ Open
Chan WL, Gao Z, Chuxi AL, Rainer T, Tang WWC, Wing YSS, Lederman Z.   +6 more
europepmc   +1 more source

Social exclusion, social isolation and the distribution of income

, 1998
Social exclusion can be distinguished from social isolation, defining social isolation as the phenomenon of non-participation (of an individual or group) in a society's mainstream institutions, while reserving 'social exclusion' for the subset of cases ...
Barry, Brian
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Interventions against loneliness and social isolation in older adults- a systematic review. [PDF]

BMC Public Health
Bergsträsser J, Schmahl T, Steinhäuser J, Goetz K.   +3 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Technology and Inpatient Care: Addressing Communication Barriers and Social Isolation. [PDF]

J Patient Exp
Amirkhani-Ardeh S, Agboji A, Fyfe T, Klassen-Ross T, Freeman S.   +4 more
europepmc   +1 more source