Results 191 to 200 of about 1,489,546 (268)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Social Issues and Emotional Distress amongst Patients with Cancer Receiving Palliative Care in a Tertiary Cancer Centre. [PDF]

Indian J Palliat Care
Rohini T, Mohan S, Jesmon J, Sreetha P, Biji MS.   +4 more
europepmc   +1 more source

Ethical, Legal and Social Issues of Digital Phenotyping as a Future Solution for Present-Day Challenges: A Scoping Review. [PDF]

Sci Eng Ethics, 2021
Tomičić A, Malešević A, Čartolovni A.   +2 more
europepmc   +1 more source

Ethical and social issues in prediction of risk of severe mental illness: a scoping review and thematic analysis. [PDF]

BMC Psychiatry
Neiders I, Mežinska S, van Haren NEM.
europepmc   +1 more source

Communicating the ethical, legal, and social issues in neurobiobanking and stroke genomic research in Africa: Project intervention tools development and evaluation procedures. [PDF]

J Stroke Cerebrovasc Dis
Ojebuyi BR, Afolami I, Adigun M, Singh A, Jenkins C, Nichols M, Wahab K, Bello A, Sarfo FS, Owolabi LF, Musbahu R, Obiako R, Akpalu A, Ogunronbi M, Olorunsogbon O, Calys-Tagoe B, Adesina D, Coleman N, Sule AG, Mande A, Uthman M, Titiloye M, Uvere E, Bukola O, Laryea R, Fakunle A, Adeleye O, Mensah N, Yusuf J, Adeniyi S, Asibey S, Omotoso L, Melikam L, Olujobi D, Oguike W, Akinyemi J, Jegede A, Kalaria R, Ovbiagele B, Owolabi M, Arulogun O, Akinyemi R.   +41 more
europepmc   +1 more source

Psychodrama Group Therapy for Social Issues: A Systematic Review of Controlled Clinical Trials. [PDF]

Int J Environ Res Public Health, 2021
López-González MA, Morales-Landazábal P, Topa G.   +2 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Students' perceptions of social issues in biology courses. [PDF]

J Microbiol Biol Educ
Tran S, Tirado J, Miyasato H, Lee SW.
europepmc   +1 more source

Elevated Inter-Brain Coherence Between Subjects With Concordant Stances During Discussion of Social Issues. [PDF]

Front Hum Neurosci, 2021
Richard C, Karić MS, McConnell M, Poole J, Rupp G, Fink A, Meghdadi A, Berka C.   +7 more
europepmc   +1 more source

Embedded Ethics in Practice: A Toolbox for Integrating the Analysis of Ethical and Social Issues into Healthcare AI Research. [PDF]

Sci Eng Ethics
Willem T, Fritzsche MC, Zimmermann BM, Sierawska A, Breuer S, Braun M, Ruess AK, Bak M, Schönweitz FB, Meier LJ, Fiske A, Tigard D, Müller R, McLennan S, Buyx A.   +14 more
europepmc   +1 more source