Results 61 to 70 of about 2,237,190 (358)

Societal and Economic Elements of Trafficking in Human Beings into the European Union

Etnoantropološki Problemi, 2016
The European Union (EU) is an early signatory of the United Nations Convention against Transnational Organized Crime. During the past decade, the EU has been undertaking various measures to conform to the "Protocol to Prevent, Suppress and Punish ...
Alfred Wong, Roxanne Gomes
doaj  

Lower social vulnerability is associated with a higher prevalence of social media-involved violent crimes in Prince George’s County, Maryland, 2018–2023

Injury Epidemiology
Background Social vulnerability may play a role in social media-involved crime, but few studies have investigated this issue. We investigated associations between social vulnerability and social media-involved violent crimes.
Jemar R. Bather, Diana Silver, Brendan P. Gill, Adrian Harris, Jin Yung Bae, Nina S. Parikh, Melody S. Goodman   +6 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Geographic distribution and demographic factors associated with use of a long-acting reversible contraceptive (LARC) in Ethiopia

Geospatial Health
Background: Increasing access to and utilization of long-acting reversible contraceptives (LARC) can prevent unintended pregnancies and reduce unmet need for family planning in Ethiopia However, LARC uptake lags behind less effective contraceptive ...
Mintesnot Tenkir Teni, Travis Loux, Ness Sandoval, Anne Sebert Kuhlmann   +3 more
doaj   +1 more source

Discussion Paper: Inclusive Education: Beyond Popular Discourses [PDF]

International Journal of Emotional Education, 2018
The popular discourse of democratic education is home to numerous myths surrounding our conceptions of what inclusion means in today’s schools. Certain beliefs like the idea that offering equal opportunities for participation to all students regardless ...
John P. Portelli, Patricia Koneeny
doaj  

Creating a More Inclusive Community through Social Justice Activism [PDF]

, 2017
As grassroots movement for social equity and justice builds on campus, RWU expands programming for Social Justice ...
Rodrigues, Jill
core   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Justice Delayed in the COVID-19 Era: Injunctions, Mootness, and Religious Freedom in the United States Legal System

Laws
The COVID-19 pandemic exposed critical deficiencies in the United States’ legal system’s handling of emergency injunctions, particularly concerning religious freedom.
Karen McGuffee, Tammy Garland, Sherah L. Basham   +2 more
doaj   +1 more source